Haifeng Jin
Country:
China
Current Affiliation:
State Key Laboratory of Cancer Biology & Institute of Xijing Digestive Diseases Hospital, the Fourth Military Medical University
Current Position:
Changle Western Road 17, Xi'an city, Shannxi Province,
Field of Research:
BIOLOGICAL SCIENCES - Biochemistry and Cell Biology - Biochemistry and Cell Biology not elsewhere classified
Research Interests:
Bioinformatics
Carcinogenesis
Systemsbiology
Drug discovery of anti-cancer
Signal transduction
Publication History:
1. Jin H, Pan Y, He L, Zhai H, Li X, Zhao L, Sun L, Liu J, Hong L, Song J, Xie H, Gao J, Han S, Li Y, Fan D. p75 neurotrophin receptor inhibits invasion and metastasis of gastric cancer. Mol Cancer Res. 2007;5(5):423-33.
2. Jin H, Pan Y, Zhao L, Zhai H, Li X, Sun L, He L, Chen Y, Hong L, Du Y, Fan D. p75 neurotrophin receptor suppresses the proliferation of human gastric cancer cells. Neoplasia. 2007;9(6):471-8.
3. Haifeng Jin, Gao Liuchun, Liu Lili, He Lijie, Li Xiaohua, Sun Li, Pan Yanglin, Hong Liu, Liang Jie, Jiugang Song, Yang Zhiping, Wu Kaichun, Fan Daiming. miR-146a mediated the transcriptive regulation of OCT1 promotes the tumorigenesis of gastric cancer. Neoplasia. 2009 (revised)
4. Haifeng Jin, Liuchun Gao, Zhipeng Wang, Lijie He, Li Sun, Xiaohua Li, Yanglin Pan, Jie Liang, Liu Hong, Jiugang Song, Kaichun Wu, Daiming Fan. R-flurbiprofen selectively induces p75NTR-dependent reversal of multidrug resistance in human gastric cancer. Clin Cancer Res. 2009 (revised)
5. Jin Haifeng, Sun Li, Wang Zhipeng, Gao Liuchun, Liu Lili, Li Xiaohua, He Lijie, Pan Yanglin, Hong Liu, Liang Jie, Yang Zhiping, Wu Qiong, Wu Kaichun, Fan Daiming. R-flurbiprofen reverses multidrug resistance, proliferation and metastasis in gastric cancer cells by p75NTR induction. Clin Cancer Res. 2009 (revised)
6. He Yuanlong, Jin Haifeng, Zhang Xiaoyin, Song Jialin, Liu Jie, Yan Li, Xie Huahong, Song Jiugang, Pan Yanglin, Wu Kaichun, Ding Jie, Fan Daiming. The inhibitory effect of p75 neurotrophin receptor on growth of human hepatocellular carcinoma cells. Cancer Lett. 2008; 8;268(1):110-9. (co-first author)
7. Jianjun Ma, Haifeng Jin, He Wang, Jianlin Yuan ,Tingyi Bao, Xue Jiang, Wei Zhang, Huadong Zhao, Libo Yao. Expression of NDRG2 in Clear Cell Renal Cell Carcinoma. Biol. Pharm. Bull. 2008; 31(7):1316-20. (co-first author)
8. He L, Jin H, Wang H, Guo C, Xie H, Yan K, Li X, Shen Q, Qiao T, Chen G, Chai N, Zhao L, Dong Q, Zheng Y, Liu J, Fan D.CIAPIN1 inhibits the growth and proliferation of clear cell renal cell carcinoma. Cancer Lett. 2008 Dec 8. [Epub ahead of print]（co-first author）
9. Hai Shi, Haifeng Jin, Dake Chu, Weizhong Wang, Jian Zhang, Changsheng Chen,Chunsheng Xu, Daiming Fan and Libo Yao. Suppression of NDRG2 is associated with induction of Myc in colorectal cancer and correlates closely with differentiation. Biol. Pharm. Bull. 2009(accepted) (co-first author)
10. Hai Shi, Haifeng Jin, Chunsheng Xu, Guanglong Dong , Qingchuan Zhao, Weizhong Wang , Hongwei Zhang, Libo Yao and Daiming Fan. Down-regulation of MSP58 inhibits the proliferation and growth of colorectal cancer cells via regulation of BRCA1-CyclinD/CDK4-p21 pathway. Cancer Sci. 2009 (revised) （co-first author）
11. Wang Zhipeng, Jin Haifeng, Li Chen, Hou ying, Mei Qibing and Fan Daiming. Heat shock protein 72 protects kidney proximal tubular cells from injury induced by Triptolide via activation of MEK/ERK pathway. Basic & Clinical Pharmacology & Toxicology 2009 (revised) （co-first author）
12. Zhipeng Wang, Haifeng Jin, Ruodan Xu, Qibing Mei, Daiming Fan. Triptolide downregulates RAC1 and the JAK/STAT3 pathway and inhibits colitis-related colon cancer progression. Gastroenrology 2009;(revised) (co-first author)
13. Zhai H, Shi Y, Jin H, Li Y, Lu Y, Chen X, Wang J, Ding L, Wang X, Fan D. Expression of calcyclin-binding protein/Siah-1 interacting protein in normal and malignant human tissues: an immunohistochemical survey. J Histochem Cytochem. 2008 Aug;56(8):765-72.
14. Hong L, Li X, Jin H, Yan L, Wu K, Ding J, Zhao Y, Guo W, Fan D. Up-regulation of tumor suppressor genes might promote the malignant phenotype of cancer cells. Med Hypotheses. 2007;69(6):1379.
15. Li X, Hong L, Zhao Y, Jin H, Fan R, Du R, Xia L, Luo G, Fan D. A new apoptosis inhibitor, CIAPIN1 (cytokine-induced apoptosis inhibitor 1), mediates multidrug resistance in leukemia cells by regulating MDR-1, Bcl-2, and Bax. Biochem Cell Biol. 2007;85(6):741-750.
16. Xiaohua Li, Yanglin Pan, Rui Fan, Haifeng Jin, Shuang Han, Jie Liu,Kaichun Wu, Daiming Fan. Adenovirus-delivered CIAPIN1 small interfering RNA inhibits HCC growth in vitro and in vivo. Carcinogenesis, 2008；29(8):1587-93.
17. Li X, Fan R, Zou X, Gao L, Jin H, Du R, Xia L, Fan D. Inhibitory effect of recombinant adenovirus carrying immunocaspase-3 on hepatocellular carcinoma. Biochem Biophys Res Commun. 2007;358(2):489-94.
18. Li X, Hao Z, Fan R, Zou X, Jin H, Pan Y, He L, Du R, Gao L, Liu J, Fan D. CIAPIN1 Inhibits Gastric Cancer Cell Proliferation and Cell Cycle Progression by Downregulating CyclinD1 and Upregulating P27. Cancer Biol Ther. 2007; 7(4) [Epub ahead of print].
19. Hong L, Zhao Y, Han Y, Guo W, Jin H, Qiao T, Che Z, Fan D. Mechanisms of growth arrest by zinc ribbon domain-containing 1 in gastric cancer cells. Carcinogenesis. 2007;28(8):1622-8.
20. Yanglin P, Lina Z, Zhiguo L, Na L, Haifeng J, Guoyun Z, Jie L, Jun W, Tao L, Li S, Taidong Q, Jianhong W, Daiming F. KCNE2, a down-regulated gene identified by in silico analysis, suppressed proliferation of gastric cancer cells. Cancer Lett. 2007;246(1-2):129-38.
21. Xiaohua Li, Yunping Zhao, Zheyi Han, Rui Fan, Haifeng Jin, Jie Liang, Rui Du, Lin Xia, Yafei Zhang, Jie Liu, Daiming Fan. RUNX3 Inhibits Growth of HCC Cells and HCC Xenografts in Mice in Combination With Adriamycin. Cancer Biology therapy, 2008 7(5):669-76.
22. Hong L, Zhao Y, Wang J, Han Y, Guo W, Jin H, Zhai H, Bai F, Zhang X, Qiao T, Chen Z, Fan D. Reversal of Multidrug Resistance of Adriamycin-resistant Gastric Adenocarcinoma Cells Through the Up-regulation of DARPP-32. Dig Dis Sci. 2008;53 (1):101-107.
23. X. Li, R. Fan, X. Zou, L. Hong, L. Gao, H. Jin, R. Du, L. He, L. Xia, and D. Fan. Reversal of multidrug resistance of gastric cancer cells by down-regulation of CIAPIN1 with CIAPIN1 siRNA. Molecular Biology, 2008; 421, (1)91-97.
24. Li X, Zhang Y, Cao S, Chen X, Lu Y, Jin H, Sun S, Chen B, Liu J, Ding J, Wu K, Fan D. Reduction of TIP30 correlates with poor prognosis of gastric cancer patients and its restoration drastically inhibits tumor growth and metastasis. Int J Cancer. 2009; 124(3):713-21.
25. Liang J, Luo G, Ning X, Shi Y, Zhai H, Sun S, Jin H, Liu Z, Zhang F, Lu Y, Zhao Y, Chen X, Zhang H, Guo X, Wu K, Fan D. Differential expression of calcium-related genes in gastric cancer cells transfected with cellular prion protein. Biochem Cell Biol. 2007;85(3):375-83.
26. Song J, Xie H, Lian Z, Yang G, Du R, Du Y, Zou X, Jin H, Gao J, Liu J, Fan D. Enhanced cell survival of gastric cancer cells by a novel gene URG4. Neoplasia. 2006;8(12):995-1002.
27. Pan Y, Zhao L, Liang J, Liu J, Shi Y, Liu N, Zhang G, Jin H, Gao J, Xie H, Wang J, Liu Z, Fan D. Cellular prion protein promotes invasion and metastasis of gastric cancer. FASEB J. 2006;20(11):1886-8.
28. Hong L, Wang J, Zhao Y, Han Z, Zhou X, Guo W, Zhang X, Jin H, Wu K, Ding J, Fan D. DARPP-32 mediates multidrug resistance of gastric cancer through regulation of P-gp and ZNRD1. Cancer Invest. 2007;25(8):699-705.
2. Jin H, Pan Y, Zhao L, Zhai H, Li X, Sun L, He L, Chen Y, Hong L, Du Y, Fan D. p75 neurotrophin receptor suppresses the proliferation of human gastric cancer cells. Neoplasia. 2007;9(6):471-8.
3. Haifeng Jin, Gao Liuchun, Liu Lili, He Lijie, Li Xiaohua, Sun Li, Pan Yanglin, Hong Liu, Liang Jie, Jiugang Song, Yang Zhiping, Wu Kaichun, Fan Daiming. miR-146a mediated the transcriptive regulation of OCT1 promotes the tumorigenesis of gastric cancer. Neoplasia. 2009 (revised)
4. Haifeng Jin, Liuchun Gao, Zhipeng Wang, Lijie He, Li Sun, Xiaohua Li, Yanglin Pan, Jie Liang, Liu Hong, Jiugang Song, Kaichun Wu, Daiming Fan. R-flurbiprofen selectively induces p75NTR-dependent reversal of multidrug resistance in human gastric cancer. Clin Cancer Res. 2009 (revised)
5. Jin Haifeng, Sun Li, Wang Zhipeng, Gao Liuchun, Liu Lili, Li Xiaohua, He Lijie, Pan Yanglin, Hong Liu, Liang Jie, Yang Zhiping, Wu Qiong, Wu Kaichun, Fan Daiming. R-flurbiprofen reverses multidrug resistance, proliferation and metastasis in gastric cancer cells by p75NTR induction. Clin Cancer Res. 2009 (revised)
6. He Yuanlong, Jin Haifeng, Zhang Xiaoyin, Song Jialin, Liu Jie, Yan Li, Xie Huahong, Song Jiugang, Pan Yanglin, Wu Kaichun, Ding Jie, Fan Daiming. The inhibitory effect of p75 neurotrophin receptor on growth of human hepatocellular carcinoma cells. Cancer Lett. 2008; 8;268(1):110-9. (co-first author)
7. Jianjun Ma, Haifeng Jin, He Wang, Jianlin Yuan ,Tingyi Bao, Xue Jiang, Wei Zhang, Huadong Zhao, Libo Yao. Expression of NDRG2 in Clear Cell Renal Cell Carcinoma. Biol. Pharm. Bull. 2008; 31(7):1316-20. (co-first author)
8. He L, Jin H, Wang H, Guo C, Xie H, Yan K, Li X, Shen Q, Qiao T, Chen G, Chai N, Zhao L, Dong Q, Zheng Y, Liu J, Fan D.CIAPIN1 inhibits the growth and proliferation of clear cell renal cell carcinoma. Cancer Lett. 2008 Dec 8. [Epub ahead of print]（co-first author）
9. Hai Shi, Haifeng Jin, Dake Chu, Weizhong Wang, Jian Zhang, Changsheng Chen,Chunsheng Xu, Daiming Fan and Libo Yao. Suppression of NDRG2 is associated with induction of Myc in colorectal cancer and correlates closely with differentiation. Biol. Pharm. Bull. 2009(accepted) (co-first author)
10. Hai Shi, Haifeng Jin, Chunsheng Xu, Guanglong Dong , Qingchuan Zhao, Weizhong Wang , Hongwei Zhang, Libo Yao and Daiming Fan. Down-regulation of MSP58 inhibits the proliferation and growth of colorectal cancer cells via regulation of BRCA1-CyclinD/CDK4-p21 pathway. Cancer Sci. 2009 (revised) （co-first author）
11. Wang Zhipeng, Jin Haifeng, Li Chen, Hou ying, Mei Qibing and Fan Daiming. Heat shock protein 72 protects kidney proximal tubular cells from injury induced by Triptolide via activation of MEK/ERK pathway. Basic & Clinical Pharmacology & Toxicology 2009 (revised) （co-first author）
12. Zhipeng Wang, Haifeng Jin, Ruodan Xu, Qibing Mei, Daiming Fan. Triptolide downregulates RAC1 and the JAK/STAT3 pathway and inhibits colitis-related colon cancer progression. Gastroenrology 2009;(revised) (co-first author)
13. Zhai H, Shi Y, Jin H, Li Y, Lu Y, Chen X, Wang J, Ding L, Wang X, Fan D. Expression of calcyclin-binding protein/Siah-1 interacting protein in normal and malignant human tissues: an immunohistochemical survey. J Histochem Cytochem. 2008 Aug;56(8):765-72.
14. Hong L, Li X, Jin H, Yan L, Wu K, Ding J, Zhao Y, Guo W, Fan D. Up-regulation of tumor suppressor genes might promote the malignant phenotype of cancer cells. Med Hypotheses. 2007;69(6):1379.
15. Li X, Hong L, Zhao Y, Jin H, Fan R, Du R, Xia L, Luo G, Fan D. A new apoptosis inhibitor, CIAPIN1 (cytokine-induced apoptosis inhibitor 1), mediates multidrug resistance in leukemia cells by regulating MDR-1, Bcl-2, and Bax. Biochem Cell Biol. 2007;85(6):741-750.
16. Xiaohua Li, Yanglin Pan, Rui Fan, Haifeng Jin, Shuang Han, Jie Liu,Kaichun Wu, Daiming Fan. Adenovirus-delivered CIAPIN1 small interfering RNA inhibits HCC growth in vitro and in vivo. Carcinogenesis, 2008；29(8):1587-93.
17. Li X, Fan R, Zou X, Gao L, Jin H, Du R, Xia L, Fan D. Inhibitory effect of recombinant adenovirus carrying immunocaspase-3 on hepatocellular carcinoma. Biochem Biophys Res Commun. 2007;358(2):489-94.
18. Li X, Hao Z, Fan R, Zou X, Jin H, Pan Y, He L, Du R, Gao L, Liu J, Fan D. CIAPIN1 Inhibits Gastric Cancer Cell Proliferation and Cell Cycle Progression by Downregulating CyclinD1 and Upregulating P27. Cancer Biol Ther. 2007; 7(4) [Epub ahead of print].
19. Hong L, Zhao Y, Han Y, Guo W, Jin H, Qiao T, Che Z, Fan D. Mechanisms of growth arrest by zinc ribbon domain-containing 1 in gastric cancer cells. Carcinogenesis. 2007;28(8):1622-8.
20. Yanglin P, Lina Z, Zhiguo L, Na L, Haifeng J, Guoyun Z, Jie L, Jun W, Tao L, Li S, Taidong Q, Jianhong W, Daiming F. KCNE2, a down-regulated gene identified by in silico analysis, suppressed proliferation of gastric cancer cells. Cancer Lett. 2007;246(1-2):129-38.
21. Xiaohua Li, Yunping Zhao, Zheyi Han, Rui Fan, Haifeng Jin, Jie Liang, Rui Du, Lin Xia, Yafei Zhang, Jie Liu, Daiming Fan. RUNX3 Inhibits Growth of HCC Cells and HCC Xenografts in Mice in Combination With Adriamycin. Cancer Biology therapy, 2008 7(5):669-76.
22. Hong L, Zhao Y, Wang J, Han Y, Guo W, Jin H, Zhai H, Bai F, Zhang X, Qiao T, Chen Z, Fan D. Reversal of Multidrug Resistance of Adriamycin-resistant Gastric Adenocarcinoma Cells Through the Up-regulation of DARPP-32. Dig Dis Sci. 2008;53 (1):101-107.
23. X. Li, R. Fan, X. Zou, L. Hong, L. Gao, H. Jin, R. Du, L. He, L. Xia, and D. Fan. Reversal of multidrug resistance of gastric cancer cells by down-regulation of CIAPIN1 with CIAPIN1 siRNA. Molecular Biology, 2008; 421, (1)91-97.
24. Li X, Zhang Y, Cao S, Chen X, Lu Y, Jin H, Sun S, Chen B, Liu J, Ding J, Wu K, Fan D. Reduction of TIP30 correlates with poor prognosis of gastric cancer patients and its restoration drastically inhibits tumor growth and metastasis. Int J Cancer. 2009; 124(3):713-21.
25. Liang J, Luo G, Ning X, Shi Y, Zhai H, Sun S, Jin H, Liu Z, Zhang F, Lu Y, Zhao Y, Chen X, Zhang H, Guo X, Wu K, Fan D. Differential expression of calcium-related genes in gastric cancer cells transfected with cellular prion protein. Biochem Cell Biol. 2007;85(3):375-83.
26. Song J, Xie H, Lian Z, Yang G, Du R, Du Y, Zou X, Jin H, Gao J, Liu J, Fan D. Enhanced cell survival of gastric cancer cells by a novel gene URG4. Neoplasia. 2006;8(12):995-1002.
27. Pan Y, Zhao L, Liang J, Liu J, Shi Y, Liu N, Zhang G, Jin H, Gao J, Xie H, Wang J, Liu Z, Fan D. Cellular prion protein promotes invasion and metastasis of gastric cancer. FASEB J. 2006;20(11):1886-8.
28. Hong L, Wang J, Zhao Y, Han Z, Zhou X, Guo W, Zhang X, Jin H, Wu K, Ding J, Fan D. DARPP-32 mediates multidrug resistance of gastric cancer through regulation of P-gp and ZNRD1. Cancer Invest. 2007;25(8):699-705.
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