weimin cai
City:
Shanghai
Country:
China
Current Affiliation:
Fudan University College of Pharmacy
Current Position:
Director
Professor
Career Highlights:
Clin Pharmacy
Field of Research:
MEDICAL AND HEALTH SCIENCES - Pharmacology and Pharmaceutical Sciences - Pharmacogenomics
Professional Memberships:
China Pharmaceutical Association
Chinese Pharmacological Association
China Hospital Association
Chinese Pharmacological Association
China Hospital Association
Notable Grants/Projects:
“Genetic Polymorphisms in Drug Metabolism Enzymes in Patients with End Stage Renal Disease”, Natural Science Foundation of China, 200,000, Jan. 2003 ~ Dec. 2005 (Principal Investigator), Funded.
“Genetic Polymorphisms in Drug Metabolism Enzymes in Patients with End Stage Renal Disease”, Natural Science Foundation of Jiangsu, 65,000, Jan. 2003 ~ Dec. 2005 (Principal Investigator), Funded.
“Study on genetic polymorphism of drug metabolizing enzymes and receptors in patients with end stage renal disease.” A Foundation for the Author of National Excellent Doctoral Dissertation of PR China (FANEDD), 350.000, 2004.1～2007.12(Principal Investigator), Funded.
“Genetic Polymorphisms in Drug Metabolism Enzymes in Patients with End Stage Renal Disease”, Natural Science Foundation of China, 200,000, Jan. 2003 ~ Dec. 2005 (Principal Investigator), Funded.
“Genetic Polymorphisms in Drug Metabolism Enzymes in Patients with End Stage Renal Disease”, Natural Science Foundation of Jiangsu, 65,000, Jan. 2003 ~ Dec. 2005 (Principal Investigator), Funded.
“Study on genetic polymorphism of drug metabolizing enzymes and receptors in patients with end stage renal disease.” A Foundation for the Author of National Excellent Doctoral Dissertation of PR China (FANEDD), 350.000, 2004.1～2007.12(Principal Investigator), Funded.
Research Interests:
Pharmacogenomics, Pharmacokinetics/dynamics, Clinical Pharmacy
Publication History:
1. Cai WM, Nikoloff DM, Pan RM, de Leon J, Fanti P, Fairchild M, Koch W, Wedlund PJ. CYP2D6 genetic variation in healthy adults and psychiatric African-American subjects: Implications for clinical practice and genetic testing. Pharmacogenomics J. 2006; March 21.
2. Chen B, Zhang WX, Cai WM. The influence of various genotypes on the metabolic activity of NAT2 in a Chinese population. Eur J Clin Pharmacol 2006; 62(5): 355~9.
3. Cai WM, Chen B, Zhang WX. Frequency of CYP2D6 *10 and *14 alleles and their influence on the metabolic activity of CYP2D6 in a healthy Chinese population. Clin Pharmacol Ther 2007；81(1)：95~8.
4. Zhang WX, Chen B, Zhang W, Yu ZC，Cai WM. Effect of MDR1 gene polymorphism on progression of end-stage renal disease. Acta Pharmacol Sin 2007; 28(4): 579～83.
5. Chen B, Zhang WX, Yu ZC，Cai WM. Determination of Mycophenolic Acid and its acyl and phenol glucuronide metabolites simultaneously in human plasma by simplified HPLC method. Analytical Letters 2007; 40: 2465~75.
6. Ma T, Cai WM, Bu Y, et al. A rapid PCR method to determine the genotypes of CYP2D6*10 alleles. Chin Pharmacol Bull 2007; 23(7):976~8.
7．Cai WM. Pharmacogenomics and individualized medicine. Chin Pharmaceutical J 2007; 42(24): 1841~1844.
8. Cai WM, Lv QZ, Zhang JZ, et al. Analysis of antibiotic use in Shanghai Second and third class hospitals in 2006. China Pharmcy 2008; 19(11): 810~3.
9. Jin Z, Zhang WX, Mao AW, Chen H, Gu ZD, Cai WM. Relationship between CYP3A5 and MDR1 gene polymorphism and blood concentration of tacrolimus in Chinese liver transplant patients. Chin Pharmaceutical J 2008；43(9)：649～53.
10. Zhang WX, Chen B, Cai WM. Inflence of UDP-glucuronosyltransferases and ABCC2 genetic polymorphisms on pharmacokinetics of mycophenolic acid and its metabolites in Chinese renal transplant. Xenobiotica （SCI，IF1.397）2008; 38(11):1422-36.
11. Z Jin, WM Zhang, B Chen, AW Mao, WM Cai. Stepwise regression analysis of the determinants of blood tacrolimus concentrations in Chinese patients with liver transplant. Med Chem 2009; 5(3):301-4.
2. Chen B, Zhang WX, Cai WM. The influence of various genotypes on the metabolic activity of NAT2 in a Chinese population. Eur J Clin Pharmacol 2006; 62(5): 355~9.
3. Cai WM, Chen B, Zhang WX. Frequency of CYP2D6 *10 and *14 alleles and their influence on the metabolic activity of CYP2D6 in a healthy Chinese population. Clin Pharmacol Ther 2007；81(1)：95~8.
4. Zhang WX, Chen B, Zhang W, Yu ZC，Cai WM. Effect of MDR1 gene polymorphism on progression of end-stage renal disease. Acta Pharmacol Sin 2007; 28(4): 579～83.
5. Chen B, Zhang WX, Yu ZC，Cai WM. Determination of Mycophenolic Acid and its acyl and phenol glucuronide metabolites simultaneously in human plasma by simplified HPLC method. Analytical Letters 2007; 40: 2465~75.
6. Ma T, Cai WM, Bu Y, et al. A rapid PCR method to determine the genotypes of CYP2D6*10 alleles. Chin Pharmacol Bull 2007; 23(7):976~8.
7．Cai WM. Pharmacogenomics and individualized medicine. Chin Pharmaceutical J 2007; 42(24): 1841~1844.
8. Cai WM, Lv QZ, Zhang JZ, et al. Analysis of antibiotic use in Shanghai Second and third class hospitals in 2006. China Pharmcy 2008; 19(11): 810~3.
9. Jin Z, Zhang WX, Mao AW, Chen H, Gu ZD, Cai WM. Relationship between CYP3A5 and MDR1 gene polymorphism and blood concentration of tacrolimus in Chinese liver transplant patients. Chin Pharmaceutical J 2008；43(9)：649～53.
10. Zhang WX, Chen B, Cai WM. Inflence of UDP-glucuronosyltransferases and ABCC2 genetic polymorphisms on pharmacokinetics of mycophenolic acid and its metabolites in Chinese renal transplant. Xenobiotica （SCI，IF1.397）2008; 38(11):1422-36.
11. Z Jin, WM Zhang, B Chen, AW Mao, WM Cai. Stepwise regression analysis of the determinants of blood tacrolimus concentrations in Chinese patients with liver transplant. Med Chem 2009; 5(3):301-4.
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Documents
| Date Uploaded | Name | Description | File | Ratings | Options |
| 2009-09-15 13:58PM | A article in CPT | cai2007cpt.pdf |
|
